Uses of heparin.

The uses of heparin to treat burn injury.

OBJECTIVES To assess the evidence for using heparin in the treatment of burn injury or the complications of burn injury in adults and children. DATA SOURCES The following databases were searched: MEDLINE (1966-current), EMBASE (1980-current), Cumulative Index to Nursing & Allied Health (CINAHL) (1982-current), The Cochrane Central Database of Controlled Trials (1995-current), Web of Science (...

Uses of intravenous immunoglobulin

Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...

A systemic review of the uses of heparin to treat burn injury.

Last year I had the opportunity to participate in a review study conducted by McMaster University Evidencebased Practice Center, Hamilton, Ontario, Canada, to assess the evidence for using heparin in the treatment of burn injury or the complications of burn injury in adults and children. Principal Investigators were Mark Oremus, PhD and Mark Hanson, MD, Med, in addition to Gurvaneet Randhawa, M...

Experimental and Clinical Therapeutic Uses of Low-Molecular-Weight Heparin/Protamine Micro/Nanoparticles

Novel Experimental and Clinical Therapeutic Uses of Low-Molecular-Weight Heparin/Protamine Microparticles

Low-molecular-weight heparin/protamine microparticles (LMW-H/P MPs) were produced as a carrier for heparin-binding growth factors (GFs) and for various adhesive cells. A mixture of low-molecular-weight heparin (MW: approximately 5000 Da, 6.4 mg/mL) and protamine (MW: approximately 3000 Da, 10 mg/mL) at a ratio of 7:3 (vol:vol) yields a dispersion of microparticles (0.5-3 µm in diameter). LMW-H/...